MAB-CHMINACA


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MAB-CHMINICA – Chemical Structural Data

As an indole based synthetic cannabinoid based on the indoazole subgroup, MAB-CHMINICA is structurally related to AB-FUBINACA also sharing a high affinity for the CB1 receptor. MAB-CHMINACA shares a similar cyclohexyle group to its core structure, however, with the difference of having a isobutyl moiety substituted at the at the tert-butyl group.

 

MAB-CHMINACA – Structure-Activity & Chemical Similarity Predictions

Being structurally similar to the synthetic cannabinoids, it is predicted that MAB-CHMINACA would have an affinity and possible efficacy at the cannabinoid receptors.

We do have some data on the binding profile seen at the CB1 receptor, provided by in vitro testes conducted at Cayman Chemical.

“It is a potent agonist of the CB1 receptorwith a binding affinity of Ki = 0.289 nM “

Known Chemical Data

Systematic (IUPAC) name N-[(2S)-1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-(cyclohexylmethyl)indazole-3-carboxamide
Chemical Name MAB-CHMINACA
Identifiers
CAS Number 1863065-92-2
ATC code 1185887-13-1
PubChem 68894304
ChemSpider C21H30N4O2
Chemical data 370.5
Formula C21H30N4O2
Molar mass 370.497 g/mo
Online Synonyms ADB-CHMINACA

1.     UNII-5BNC061EBB

2.     Adb-chminaca, (+/-)-

3.     Mab-chminaca, (+/-)-

4.     5BNC061EBB

5.     1H-Indazole-3-carboxamide, N-(1-(aminocarbonyl)-2,2-dimethylpropyl)-1-(cyclohexylmethyl)-

6.     N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide

7.     1863065-92-2

8.     ADB-CHMINACA

 

MAB-CHMINACA – Discovery, History & Research

Discovery

As part of the ever-growing research chemical movement including many novel cannabinoid synthetic molecules. MAB-CHMINACA was first identified in patent WO2009106980 A3 by Pfizer Inc. back in February 2009 with a publication date only a few months later in October of the same year/

History

Since it patent and general discovery online there has been some moderate discussion about its usage. It was described as a “Indazole Derivative” and, as such would have found its way into CB1 receptor binding laboratory analysis interested in the effects of synthetic cannabinoids. Since then, it has had some interested by the scientific community and also by the law enforcement of some countries looking to ban its sale online. Some of the more prominent western countries began to ban the substance from around 2104 – 2015, after several toxicity reported deaths.

Research

Much of the research conducted on MAB-CHMINACA has been mainly about its discovery in the online illicit market place, with only a few studies discussing its binding profile.

For more information on some of the more notable papers, please see below:

Cayman Chemical –  “MAB-CHMINACA”

https://www.google.com/patents/WO2009106980A3

10.1007/s11419-015-0264-y

10.1007/s11419-015-0272-y

26154784

27227269

http://www.aapcc.org/press/43/

http://www.adph.org/news/assets/150511.pdf

https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2014/november/cannabinoider-foreslas-bli-klassade-som-halsofarlig-vara/

http://www.cnb.gov.sg/Libraries/CNB_Newsroom_Files/CNB_NR_-_30_Apr_2015.sflb.ashx

https://www.admin.ch/opc/de/classified-compilation/20101220/index.html

 

Key Areas of Research

Samples of MAB-CHMINACA to purchase online may be used in the following scientific applications.  

  • As a forensic sample and/or for forensic chemical catalogues.
  • As a reference sample for Toxicology laboratories.
  • As a chemical reagent and/or intermediate
  • Pharmaceutical Intermediate
  • As a research chemical sample within studying pharmacology of receptor binding assays.
  • Affinity and Efficacy Receptor profiling profiling, specifically at the cannabinoid receptor subgroup.
  • Reference sample for the application within future therapeutic compounds
  • Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment

MAB-CHMINACA – Online Anecdotal Reports

There are several online discussions where people are confused between MAB-CHMINICA & ADB-CHIMINACA. As these two are the same chemical but can often be confused in the literature.

Further discussion revolves around MAB-CHMINICA reviews, erowid and wiki pages, with more MAB-CHMINICA dose chat and the obvious MAB-CHMINICA experience and effects anecdotal reports.

Forum links to anecdotal discussion by those who are able to buy MAB-CHMINACA crystals online.

Reddit.com

BlueLight.org

ukchemicalresearch.org

Chemical Safety, Legality & Indented Use

Intended use

This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.

Legality

It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.

Chemical Safety

This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.

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