Nitracaine


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Nitracaine – Chemical Structural Data

Being a structural analogue to Dimethocaine, Nitracaine is a nitrogenated analogue of Dimethocaine.

Nitracaine – Structure-Activity & Chemical Similarity Predictions

Based on the similarities of Dimethocaine it is belived that Nitracaine is similar in activity with binding to the dopamine transporter and possibly the noradrenaline transporter too.

However, there does not seem to be any formal publication outlining the exact receptor affinity and efficacy of Nitracaine.

Known Chemical Data

Systematic (IUPAC) name (3-Diethylamino-2,2-dimethylpropyl)-4-nitrobenzoate
Chemical Name Nitracaine
Identifiers
CAS Number 1648893-21-3
ATC code
PubChem
ChemSpider 29341792
Chemical data
Formula C16H24N2O4
Molar mass 308.37 g/mol
Online Synonyms Nitracaine

UNII-B8ZB08WI9O

B8ZB08WI9O

ZINC96024536

 

Nitracaine – Discovery, History & Research

Discovery

The first formal mention of Nitracaine in the literature dates back to March 2014, with analysis of test purchases from online research chemical vendors. With scientists mentioning Nitracaine alongside other chemicals as instrumentation for detecting a broad range of compounds was needed, in light of new drug synthesis within clandestine Chinese laboratories.

History

Since 2014, there has been availability of Nitracaine on the research chemical market with the freebase version being offered online with rapid home delivery. Discussion has described Nitracaine as a stimulant similar to Dimethocaine with local anaesthetic properties.

Research

There is sparse research on Nitracaine alone. The research that does exists, shows the characterisation of a novel compound and it’s chemical composition and catalogue numbers. However, in July 2014, a team at the St Jame’s Hospital in Dublin, Ireland, published a paper discussing the “syntheses, characterization and in vitro metabolism” of three research chemicals, one of which was Nitracaine.

Below you may find some of the key publications for Nitracaine:

24574100

25844048

New Synthetic Drugs Database

 

Key Areas of Research

Samples of Nitracaine to purchase online may be used in the following scientific applications.  

  • As a forensic sample and/or for forensic chemical catalogues.
  • Dopamine transporter research.
  • Local anaesthetic compounds of interest.
  • As a reference sample for Toxicology laboratories.
  • As a chemical reagent and/or intermediate
  • Pharmaceutical Intermediate
  • As a research chemical sample within studying pharmacology of receptor binding assays.
  • Affinity and Efficacy Receptor profiling.
  • Reference sample for the application within future therapeutic compounds
  • Pure reference standard for chemical analytical libraries using HPLC, FTIR, NMR and GC/MS equipment

Nitracaine – Online Anecdotal Reports

Nitracaine is not very well studied in controlled laboratory settings. However, since Nitracaine’s availability online, customers from the UK and other western countries have sought it out for their anecdotal reports.

Online forums are littered with Nitracaine reviews and comparisons with other similar research chemicals. Nitracaine vs Synthecaine can be found as a common discussion alongside the smoking Nitracaine discussiong and further dosage and experiences.

Below you may find some of the most relevant informal informational sources.

Forum links to anecdotal discussion by those who are able to buy [RC] crystals online.

Reddit.com

BlueLight.org

drugs-forum.com

ukchemicalresearch.org

Chemical Safety, Legality & Indented Use

Intended use

This is a research chemical compound. Sold as an analytical standard, reagent or laboratory tool for in vitro (outside a living organism) research only. This compound is not for human consumption or any form or in vivo research.

Legality

It is the sole responsibility of the purchaser to ensure this compound is legal to purchase and import for research chemical purposes in their country.

Chemical Safety

This compound is intended to be used in strict laboratory conditions, following all proper precautionary protocol for any novel and untested chemical. The toxicological and physiological action of this compound have not been assessed and so extreme caution should be observed when handling this compound. Please follow proper health and safety guidelines, in a well ventilated and well equipped laboratory when handling this compound.

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